ISSN 1662-4009 (online)

ey0016.15-14 | (1) | ESPEYB16

15.14. Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient

Beumer Joep , Artegiani Benedetta , Post Yorick , Reimann Frank , Gribble Fiona , Nguyen Thuc Nghi , Zeng Hongkui , Van den Born Maaike , Van Es Johan H , Clevers Hans

To read the full abstract: Nature Cell Biology 20,909–916 (2018)Produced by scattered Enteroendocrine cells (EECs)found along the length of the intestinal epithelium, gut hormones generate signals related to the rate of nutrient absorption, the composition of the luminal milieu and the integrity of the epithelial barrier. To study these rare cells, these authors combined the te...